Glycolysis is the biochemical pathway by which glucose is converted into pyruvate via fructose-1,6-bisphosphate. A sequence of ten enzymatic reactions, glycolysis generates 2 mol ATP/mol of glucose. Glycolysis is the main source of energy for most anaerobic organisms. In aerobic organisms, in addition to providing some ATP, glycolysis plays the role of transforming glucose, as well as some other sugars, into the substrate of oxidative degradation.
Glycolysis is the quintessential biochemical pathway. Glycolysis is not only important in MCAT review for itself, but also as a model for enzymatic mechanisms and their underlying organic chemistry. Additionally, glycolysis is a model for the regulation of biochemical pathways in the context of physiological integration.
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Conceptual Vocabulary for Glycolysis