The exons are the regions within a gene left behind in RNA processing after the introns are removed that are transcribed to the final messenger mRNA. Exon shuffling describes a hypothetical process in evolution whereby the exons within a gene or between two genes become mixed. Because many exons encode discrete protein domains (structural or functional units), it is hypothesized that new proteins arose in evolution by the shuffling of exons. Within this hypothesis, the evolution of new genes has often proceeded by the recombination or exclusion of exons. Exon shuffling is a probable evolutionary mechanism for the evolutionary appearance of functionally related enzymes. As a further example, the LDL receptor is an excellent example of a mosaic protein whose gene appears to have been assembled by the evolutionary process of exon shuffling.
The WikiPremed MCAT Course is a comprehensive course in the undergraduate level general sciences. Undergraduate level physics, chemistry, organic chemistry and biology are presented by this course as a unified whole within a spiraling curriculum. Please read our policies on Privacy and Shipping & Returns. Contact Us. MCAT is a registered trademark of the Association of American Medical Colleges, which does not endorse the WikiPremed Course. WikiPremed offers the customers of our publications or our teaching services no guarantees regarding eventual performance on the MCAT.
WikiPremed is a trademark of Wisebridge Learning Systems LLC. The work of WikiPremed is published under a Creative Commons Attribution NonCommercial ShareAlike License. There are elements of work here, such as a subset of the images in the archive from WikiPedia, that originated as GNU General Public License works, so take care to follow the unique stipulations of that license in printed reproductions.