The biosynthetic transformation of acetyl CoA into the isoprene derived squalene opens cholesterol synthesis. Cholesterol modulates the fluidity of eukaryotic membranes and steroid hormones are derived from cholesterol. Also, bile salts are polar derivatives of cholesterol released by the gall bladder to solubilize dietary lipids.The biosynthesis of cholesterol from squalene (six isoprene units) begins with epoxide formation to form squalene 2,3-epoxide. Multiple ring formation in squalene 2,3 epoxide is triggered by epoxide ring opening.












The WikiPremed MCAT Course is a comprehensive course in the undergraduate level general sciences. Undergraduate level physics, chemistry, organic chemistry and biology are presented by this course as a unified whole within a spiraling curriculum. Please read our policies on Privacy and Shipping & Returns.  Contact Us. MCAT is a registered trademark of the Association of American Medical Colleges, which does not endorse the WikiPremed Course. WikiPremed offers the customers of our publications or our teaching services no guarantees regarding eventual performance on the MCAT.


Creative Commons License
WikiPremed is a trademark of Wisebridge Learning Systems LLC. The work of WikiPremed is published under a Creative Commons Attribution NonCommercial ShareAlike License. There are elements of work here, such as a subset of the images in the archive from WikiPedia, that originated as GNU General Public License works, so take care to follow the unique stipulations of that license in printed reproductions.