Viscous resistance applies, and thus Poiseuille's Law applies, and also turbulance is possible in the circulation, which is a deviation from ideal fluid behavior.
Despite deviation from ideal flow, the physics governing the flow of an ideal fluid is definitely helpful for understanding the behavior of fluid in the circulatory system. For example, the continuity of volume flux roughly describes the relationship between the total flow diameter in arteries, arterioles, capillaries and flow speed through those areas. Reasons that the relationship is not exact include the elasticity of blood vessels and the fact that the cardiovascular system is not closed.
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