Integrated SequencePhysics Chemistry Organic Biology

Web Resources

Kimball's Biology Pages - G-Protein-Coupled Receptors (GPCRs)
Example of a transmembrane protein receptor.

The Medical Biochemistry Page - Signal Transduction
Excellent, comprehensive (somewhat advanced) discussion of a very important topic for the MCAT. Don't let the advanced material intimidate you away from the main concepts. You don't have to memorize everything. Working to be able comfortably comprehend discussions at this level, not knowing everything beforehand, is a primary task for MCAT preparation.

  click if a link is broken

Special points of emphasis

Biological Membranes

The Endocrine System

Cyclic AMP is the second messenger in signal coupling with glucagon and epinephrine to stimulate glycogen breakdown. Glucagon is a peptide hormone synthesized and secreted from α-cells of the islets of Langerhans of the pancreas. Epinephrine is a catecholamine synthesized by the adrenal medulla. Both hormones raise blood glucose as part of their effect. To signal the cell, these hormones activate adenylate cyclase, an enzyme associated with the plasma membrane, which catalyzes the conversion of ATP into Cyclic AMP. Cyclic AMP then serves as a second messanger within the cell.

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