Integrated SequencePhysics Chemistry Organic Biology

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Integration of Metabolism

The Endocrine System

The Musculoskeletal System

The Cardiovascular System

The biosynthesis of steroids begins with epoxide formation in the terpene squalene to form squalene 2,3-epoxide. Multiple ring formation in squalene 2,3 epoxide is triggered by epoxide ring opening.


The Endocrine System

The Digestive System and Nutrition

Vitamin D3 is a derivative of cholesterol (dehydration followed by photochemical elimination/cleavage). Bile acids and bile salts are derivatives of cholesterol (oxidation of side chain and additional hydroxyl groups on the rings; bile salts are amide derivatives of bile acids with detergent properties).

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